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Intratumor adoptive transfer of IL-12 mRNA transiently engineered antitumor CD8 + T cells

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The plSAM plasmid contains a core component named SAM, which consists of the signal peptide (SPusp45), the propeptide (PS), the multiple clone site (MCS), a designed M cell-targeting peptide (Mtp), and the peptidoglycan-binding domain of AcmA (cA domain)